Cohort study links sleep changes to cognitive decline
A cohort study in America has linked disturbed sleep with
preclinical signs of Alzheimer's disease.
Frequent awakenings and lying awake on a regular basis have been
linked to higher levels of markers in the brain plaques, which is a
common indication of Alzheimer's disease.
The study, which was conducted by Yo-El Ju, MD, of Washington
University School of Medicine in St. Louis, and colleagues, found
beta-amyloid plaques that build up in the brains of Alzheimer's
patients in some cognitively normal people. There was evidence that
this build up could be associated with sleep disruption.
Judy Willis, MD, an educator and neurologist in Santa Barbara,
California, and a member of the neurology academy said: "There is
no cure or even strong support for any treatment that can reverse
the development of amyloid plaques in humans once they form."
However, studies in mice have found that interfering with their
sleep led to increases in amyloid pathology. This is an indication
that improved sleep might lead to better mental health.
Posted by Elizabeth Mewes